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Breastfeeding and Mental Health

  • Kris Haukoos
  • Feb 10
  • 3 min read

Updated: Apr 28


A woman with postpartum depression and anxiety looks for medications that are safe while breastfeeding. She lives in Denver, CO and Eustis, FL.

Taking Antidepressants While Breastfeeding: What You Need to Know


Let’s be real for a second: the "fourth trimester" of pregnancy is no joke. Between the diaper changes, the lack of sleep, and the constant feeding, your brain is doing a lot of heavy lifting.

If you’re feeling more than just the "baby blues," you might be thinking about how to coordinate your breastfeeding and mental health. If antidepressants are recommended, you may be considering that option. But then the worry kicks in: Is this safe?


The short answer is: Yes, in most circumstances, it is safe. Here is the lowdown on how it works, what the experts say, and how to take care of both you and your little one.


The Big Question: Does the medicine get into your breast milk?


Yes, almost any medicine you take will show up in your breast milk in tiny amounts. However, "tiny" is the key word here.


Doctors look at something called the Relative Infant Dose (RID). This is just a fancy way of measuring how much medicine is transferred to the baby through breastmilk.


  • The "Safe" Zone: Experts usually feel comfortable if the baby gets less than 10% of the mom's dose.

  • The Reality: Most common antidepressants (like SSRIs) stay way below that. Most SSRIs don't show up in the baby's blood at all. Sertraline, also called Zoloft, is one of the SSRIs that is commonly used by breastfeeding mothers.


Why Your Mental Health Matters, Too


It’s easy to focus 100% on the baby, but you are the "engine" of the family. If the engine isn't running well, the whole car struggles. Untreated depression can make it harder to bond with your baby or even keep up with breastfeeding. Taking care of your mental health isn't "selfish"—it’s part of being a great parent. A healthy, happy mom is one of the best things you can give your child.


Which Meds are the "Go-To" Choices?


While you should always talk to your doctor, some medicines have been studied more than others.

  • Sertraline (Zoloft): This is often the first choice because very little gets into the milk.

  • Paroxetine (Paxil): Another one that tends to stay at very low levels in breast milk. Because this medication is harder to stop later, this may not be the choice your provider makes.

  • A Note on Fluoxetine (Prozac): This one stays in your system longer. Some doctors prefer others, but if Prozac is what works for you, many experts still say it's okay to keep using it.

Pro Tip: If you found a medicine that worked for you in the past, tell your doctor! It’s often better to use what you know works than to try something new during a stressful time.

What Should I Watch For?


Even though these meds are generally safe, it’s always smart to keep an eye on your baby.

Look for:

  • Extra sleepiness (more than usual!)

  • Being very fussy or irritable

  • Not wanting to eat

  • Not gaining weight like they should

If you see these things, don't panic. Just call your pediatrician and let them know what's going on.


Breastfeeding and Mental Health: Resources and Further Reading


You don't have to figure this out alone. Check out these trusted spots for more info:

 
 
 

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